Metronidazole + SRP vs SRP
Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether metronidazole + SRP changes percentage of closed pockets compared with SRP (very low certainty).
3 findings from 1 review
- Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomesLong-term (≥ 1 year)MD -12.20 [-29.23, 4.83]1 study · 22 participantsVery low
- Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomesIntermediate-term (> 3 months to < 1 year)MD -7.00 [-23.57, 9.57]1 study · 22 participantsGRADE not reported
- Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomesShort-term (≤ 3 months)MD -2.56 [-12.33, 7.22]2 studies · 51 participantsGRADE not reported