Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

160/4.5 mcg BDF single inhaler therapy vs current best practice

Rate of exacerbations requiring systemic corticosteroids · adults with asthma not well controlled on ICS

160/4.5 mcg BDF single inhaler therapy probably leads to lower patients with exacerbations treated with oral steroids compared with current best practice (moderate certainty).

1 finding from 1 review

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including… 2013 · Cochrane Headline outcomes only
OR 0.83 [0.7, 0.98]
8 studies · 8841 participants
Moderate

Single inhaler therapy vs fixed dose ICS

Rate of exacerbations requiring systemic corticosteroids · adults with asthma not well controlled on ICS

Single inhaler therapy leads to lower patients with exacerbations treated with oral steroids compared with fixed dose ICS (high certainty).

1 finding from 1 review

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including… 2013 · Cochrane Headline outcomes only
OR 0.54 [0.45, 0.64]
4 studies · 4280 participants
High