Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Infectious Diseases

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No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Single dose primaquine at 0.75 mg/kg vs no primaquine, with artemisinin partner,

Participants with severe haemolysis · adults and children with malaria being treated with artemisinin combination treatment

1 finding from 1 review

Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
GRADE not reported

Single dose primaquine at 0.4 to 0.5 mg/kg vs no primaquine, with artemisinin partner,

Participants with severe haemolysis · adults and children with malaria being treated with artemisinin combination treatment

Single dose primaquine at 0.4 to 0.5 mg/kg showed no clear difference in participants with severe haemolysis compared with no primaquine, with artemisinin partner, (low certainty).

1 finding from 1 review

Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission 2018 · Cochrane Headline outcomes only
RR 1.54 [0.38, 6.3]
2 studies · 260 participants
Low

Single dose primaquine at 0.2 to 0.25 mg/kg vs no primaquine, with artemisinin partner,

Participants with severe haemolysis · adults and children with malaria being treated with artemisinin combination treatment

Single dose primaquine at 0.2 to 0.25 mg/kg showed no clear difference in participants with severe haemolysis compared with no primaquine, with artemisinin partner, (moderate certainty).

1 finding from 1 review

Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission 2018 · Cochrane Headline outcomes only
RR 0.98 [0.69, 1.39]
4 studies · 752 participants
Moderate