Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Common Mental Disorders

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No studies found 3 · 75%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

S‐adenosyl methionine as monotherapy vs tricyclic antidepressants (TCAs)

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

S‐adenosyl methionine as monotherapy may leads to lower acceptability. Participants experiencing troublesome adverse effects… compared with tricyclic antidepressant agent (low certainty).

1 finding from 1 review

S‐adenosyl methionine (SAMe) for depression in adults 2016 · Cochrane Headline outcomes only
RR 0.68 [0.52, 0.88]
3 studies · 604 participants
Low

S‐adenosyl methionine as monotherapy vs SSRI

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

The review found no eligible studies for this question.

1 finding from 1 review

S‐adenosyl methionine (SAMe) for depression in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

S‐adenosyl methionine as adjunctive treatment vs placebo

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

The review found no eligible studies for this question.

1 finding from 1 review

S‐adenosyl methionine (SAMe) for depression in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

S‐adenosyl methionine as monotherapy vs placebo

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

The review found no eligible studies for this question.

1 finding from 1 review

S‐adenosyl methionine (SAMe) for depression in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found