Metronidazole vs placebo
Participant‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
- no estimate extracted3 studies · 252 participantsModerate
Findings
What do systematic reviews say?
6 questions · 6 findings · 1 reviews · Skin
No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 2 · 33.3%High 2 · 33.3%
Topical metronidazole vs oral (oxy)tetracycline
Participant‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
- no estimate extracted3 studies · 182 participantsModerate
Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Azelaic acid vs topical metronidazole
Participant‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
- no estimate extracted3 studies · 491 participantsLow
Topical ivermectin vs topical metronidazole
Participant‐assessed improvement in rosacea severity · Participants with rosacea
Topical ivermectin leads to higher participant‐assessed improvement in rosacea severity Likert scale ‐… compared with topical metronidazole (high certainty).
1 finding from 1 review
- RR 1.14 [1.07, 1.22]1 study · 962 participantsHigh
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Participant‐assessed improvement in rosacea severity · Participants with rosacea
Doxycycline 40 mg + azelaic acid gel showed no clear difference in participant‐assessed improvement in rosacea severity Excellent… compared with doxycycline 40 mg + metronidazole gel (high certainty).
1 finding from 1 review
- RR 1.05 [0.79, 1.4]1 study · 207 participantsHigh