Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 24 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)

1 finding from 1 review

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes
24 hours
The median pain at 24 hours in the control group was 3 (range 0 to 10); the median pain at 24 hours in the intervention group was the same (median 3, range 0 to 8). P = 0.219 (Mann-Whitney U).
1 study · 72 participants
Low

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 48 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)

1 finding from 1 review

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes
48 hours
Median pain at 48 hours 1 (range 0 to 9) in the antibiotic group versus 2 (range 0 to 10) in the control group. P = 0.242 (Mann-Whitney U).
1 study · 72 participants
GRADE not reported

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 72 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)

1 finding from 1 review

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes
72 hours
The median pain at 72 hours in the control group was 0 (range 0 to 10); the median pain at 72 hours in the intervention group was the same (median 0, range 0 to 7). P = 0.116 (Mann-Whitney U).
1 study · 72 participants
Low