Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Bone, Joint and Muscle Trauma

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 0 · 0%High 1 · 33.3%

NSAIDs vs combination (paracetamol and opioid) analgesic

Little or no pain at 1 to 3 days · people with acute soft tissue injury, such as ankle sprain

It is very uncertain whether NSAID changes little or no pain at 1 to 3 days compared with combination (paracetamol and opioid) analgesic (very low certainty).

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
RR 1.49 [0.65, 3.4]
2 studies · 149 participants
Very low

NSAIDs vs opioid

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · acute soft tissue injury

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 706 participants
Low

NSAIDs vs paracetamol

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with acute soft tissue injury, such as ankle sprain

1 finding from 1 review

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1232 participants
High