Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

Ignored "PE": search terms need at least 3 characters.

465 questions · 491 findings · 45 reviews

No studies found 117 · 23.8%GRADE not reported 35 · 7.1%Very low 131 · 26.7%Low 133 · 27.1%Moderate 61 · 12.4%High 14 · 2.9%

Recombinant human soluble thrombomodulin vs heparin

Mortality from any cause (15‐day and 30‐day in‐hospital) · DIC

It is very uncertain whether recombinant human soluble thrombomodulin changes mortality from any cause (15‐day and 30‐day in‐hospital) compared with heparin (very low certainty).

1 finding from 1 review

Intervention not reported

Other thrombotic events: venous thrombosis (up to 48 hours after CC) · children with congenital heart disease undergoing CC

The intervention showed no clear difference in other thrombotic events: venous thrombosis (up to 48 hours after CC) (moderate certainty).

1 finding from 1 review

Aspirin vs placebo

Adverse events in the mother ‐ Bleeding · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

It is very uncertain whether aspirin changes adverse events in the mother ‐ Bleeding compared with placebo (very low certainty).

1 finding from 1 review