What do systematic reviews say?

Perioperative chemotherapy vs primary surgery

Perioperative chemotherapy leads to lower overall survival among all patients compared with primary surgery (high certainty).

• Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach,… 2013 · Cochrane Headline outcomes only
  HR 0.81 [0.73, 0.89]
  14 studies · 2422 participants
  High