Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Overall rate of adverse events · adults with a history of SAD who do not fulfil criteria for major depressive disorder

Bupropion XL showed no clear difference in overall rate of adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Second‐generation antidepressants for preventing seasonal affective disorder in adults 2019 · Cochrane Headline outcomes only
RR 1.02 [0.97, 1.08]
3 studies · 1048 participants
Moderate