What do systematic reviews say?

Intervention not reported

• Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
  1.02 [0.87, 1.19]
  4 studies · 447 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes overall postoperative morbidity (very low certainty).

• Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
  RR 1.16 [0.67, 2.02]
  2 studies · 351 participants
  Very low

Intervention not reported

The intervention showed no clear difference in overall postoperative morbidity (low certainty).

• Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery 2023 · Cochrane Headline outcomes only
  RR 1.2 [0.98, 1.48]
  4 studies · 893 participants
  Low

Laparoscopic vs open surgery

It is very uncertain whether laparoscopic changes early overall morbidity (30 postoperative days) compared with open surgery (very low certainty).

• Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
  RR 1.46 [0.51, 4.2]
  1 study · 113 participants
  Very low

Laparoscopic vs open surgery

It is very uncertain whether laparoscopic changes late overall morbidity (after the first 30 postoperative days:… compared with open surgery (very low certainty).

• Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
  RR 0.6 [0.26, 1.38]
  1 study · 93 participants
  Very low