What do systematic reviews say?

Nonavalent HPV vaccine vs quadrivalent HPV vaccine

Nonavalent HPV vaccine leads to higher overall local/injection site adverse events at 15‐day compared with quadrivalent HPV vaccine (high certainty).

• Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
  RR 1.07 [1.05, 1.08]
  3 studies · 15863 participants
  High