Summary of findings table ‐ Calaspargase (11 doses, 2500 IU/m2, IV) vs PEG‐asparaginase (16 doses, 2500 IU/m2, IV)
Osteonecrosis · children and adolescents (< 18 years of age) with first‐line ALL
Summary of findings table ‐ Calaspargase (11 doses, 2500 IU/m2, IV) showed no clear difference in osteonecrosis compared with PEG‐asparaginase (16 doses, 2500 IU/m2, IV) (low certainty).
1 finding from 1 review
- PEG‐asparaginase treatment regimens for acute lymphoblastic leukaemia in children: a network meta‐analysis 2023 · Cochrane Headline outcomes onlyRR 0.63 [0.15, 2.56]1 study · 223 participantsLow