Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Keratinocyte growth factor (KGF; palifermin or repifermin), intravenous vs placebo

Oral pain · Adults with cancer receiving treatment

Keratinocyte growth factor (KGF; palifermin or repifermin),… showed no clear difference in oral pain (mean pain score, 0 to 4 scale) compared with placebo; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes
RT to head and neck with cisplatin/fluorouracil
MD -0.12 [-0.27, 0.02]
2 studies · 374 participants
GRADE not reported

GM-CSF vs placebo or no treatment

Oral pain · Adults with cancer receiving treatment

Granulocyte-macrophage colony-stimulating factor (GM-CSF) showed no clear difference in oral pain (mean pain score, 0 to 10 scale) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes
BMT/SCT after conditioning for haematological cancers
MD 0.60 [-0.85, 2.05]
1 study · 90 participants
GRADE not reported