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What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 6 findings · 2 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 3 · 50%Very low 1 · 16.7%Low 1 · 16.7%Moderate 1 · 16.7%High 0 · 0%

Oral care protocol vs usual care or no treatment

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Oral care protocol showed no clear difference in oral mucositis (moderate to severe) compared with no treatment/usual care; GRADE not reported.

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Oral mucositis (moderate to severe) · All patients with cancer who are receiving treatment

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… showed no clear difference in oral mucositis (moderate to severe) compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (low certainty).

3 findings from 1 review