Vitamin A or retinoids (systemic or topical; incl. 13-cis-retinoic acid, acitretin) vs placebo or no treatment
Malignant transformation (oral cancer development) · People with a diagnosis of oral leukoplakia
It is very uncertain whether vitamin A or retinoids (systemic or topical; incl. 13-cis-retinoic… changes oral cancer development compared with placebo or no treatment (very low certainty).
1 finding from 1 review
- Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes24 months (treatment lasted 12 months)RR 0.11 [0.01, 2.05]1 study · 85 participantsVery low