Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Gynaecology and Fertility

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No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

LOD vs medical interventions

Harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of participants: 332 (2 RCTs) Harms: OHSS rates at 6 months ‐ LOD vs gonadotrophins N of participants: 33 (1 RCT) · Women with symptoms of PCOS

LOD probably leads to lower harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of… compared with medical interventions (moderate certainty).

1 finding from 1 review

Ovarian surgery for symptom relief in women with polycystic ovary syndrome 2017 · Cochrane Headline outcomes only
OR 0.05 [0.01, 0.36]
Studies not reported
Moderate

LOD of one ovary (unilateral) vs LOD of both ovaries (bilateral)

OHSS · women with anovulatory PCOS and CC resistance

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LOD with and without medical ovulation vs medical ovulation induction alone

OHSS · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation may leads to lower OHSS compared with medical ovulation induction alone (low certainty).

1 finding from 1 review

Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome 2020 · Cochrane Headline outcomes only
Peto OR 0.25 [0.07, 0.91]
8 studies · 722 participants
Low