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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Subcutaneous omalizumab + steroid vs placebo + steroid (stable steroid)

Number of participants with at least one exacerbation Severe asthma (16 to 32 weeks) · people with asthma

Subcutaneous omalizumab + steroid showed no clear difference in number of participants with at least one exacerbation Severe asthma… compared with placebo + steroid (stable steroid) (low certainty).

1 finding from 1 review

Subcutaneous omalizumab + steroid vs placebo + steroid (stable steroid)

Exacerbations (number of people experiencing ≥ 1 exacerbations) · people with asthma

Subcutaneous omalizumab + steroid probably leads to lower number of participants with at least one exacerbation Moderate to… compared with placebo + steroid (stable steroid) (moderate certainty).

1 finding from 1 review