Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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Lamotrigine plus ASMs vs placebo plus ASMs

50% or greater reduction in seizure frequency · Lennox‐Gastaut syndrome, any age

Lamotrigine plus ASMs leads to higher number of participants with ≥ 50% median reduction in all seizures compared with placebo plus ASMs (high certainty).

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
RR 2.12 [1.19, 3.76]
1 study · 167 participants
High