Findings

What do systematic reviews say?

4 questions · 7 findings · 1 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 57.1%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Adults: higher dose/longer course vs lower dose/shorter course

Exacerbations · Adults with acute asthma

It is very uncertain whether adults: higher dose/longer course changes new exacerbation in compared with lower dose/shorter course (very low certainty).

2 findings from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.98 [0.17, 5.56]
2 studies · 55 participants
Very low
Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.62 [0.23, 1.68]
3 studies · 122 participants
Low

Adults: prednisolone vs dexamethasone

Exacerbations · Adults with acute asthma

It is very uncertain whether adults: prednisolone changes new exacerbation during compared with dexamethasone (very low certainty).

2 findings from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.32 [0.39, 4.47]
1 study · 200 participants
Very low
Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.85 [0.43, 7.96]
1 study · 200 participants
Very low

Children: higher dose/longer course vs lower dose/shorter course

Exacerbations · children with acute asthma

Children: higher dose/longer course showed no clear difference in new exacerbation during compared with lower dose/shorter course (low certainty).

2 findings from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.38 [0.25, 7.47]
2 studies · 231 participants
Low
Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 2.17 [0.67, 7.01]
1 study · 100 participants
Very low

Children: prednisolone vs dexamethasone

Exacerbations · children with acute asthma

Children: prednisolone showed no clear difference in new exacerbation during compared with dexamethasone (low certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.85 [0.54, 1.34]
4 studies · 981 participants
Low