What do systematic reviews say?

SGLT2i vs placebo

SGLT2i showed no clear difference in myocardial infarction (fatal or non‐fatal) compared with placebo (high certainty).

• Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose co‐transporter‐2… 2021 · Cochrane Headline outcomes only
  OR 0.97 [0.84, 1.12]
  2 studies · 15266 participants
  High