Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 2 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Patient Global Impression of Change much or very much improved · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PGIC very much improved · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Patient Global Impression of Change much or very much improved · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in much or very much improved on PGIC during longest compared with placebo (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 1.06 [0.76, 1.49]
1 study · 179 participants
Low

PGIC very much improved · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in very much improved on PGIC during longest compared with placebo (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 1.82 [0.89, 3.72]
1 study · 179 participants
Low