Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Skin

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Methylprednisolone plus azathioprine vs methylprednisolone plus dapsone

Mortality at 1 year · bullous pemphigoid

It is very uncertain whether methylprednisolone plus azathioprine changes mortality at 1 year compared with methylprednisolone plus dapsone (very low certainty).

1 finding from 1 review

Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only
RR 0.33 [0.04, 3.01]
1 study · 54 participants
Very low

Clobetasol propionate cream vs prednisone

Mortality at 1 year · bullous pemphigoid

Clobetasol propionate cream showed no clear difference in mortality at 1 year compared with oral prednisone (low certainty).

1 finding from 1 review

Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only
RR 0.73 [0.53, 1.01]
1 study · 341 participants
Low

Doxycycline vs prednisolone

Treatment‐related mortality at 1 year (mITT) · bullous pemphigoid

Doxycycline probably leads to lower treatment‐related mortality at 1 year (mITT) compared with prednisolone (moderate certainty).

1 finding from 1 review

Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only
RR 0.25 [0.07, 0.89]
1 study · 234 participants
Moderate