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Evidence found and GRADE certainty

2 questions · 3 findings · 1 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Vitamin D vs placebo or control

Mortality (all cause) · Adults (general population)

Meta-analysis of randomised trials of vitamin D supplementation for Mortality (all cause) (Vitamin D2, general population): RR 1.04 (95% CI 0.97 to 1.11), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

2 findings from 1 review

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

All cause mortality · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for All cause mortality: HR 0.72 (95% CI 0.66 to 0.78), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review