Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Injuries

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Anaerobic coverage only vs gram‐positive and gram‐negative coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 160 participants
Very low

Anaerobic coverage only vs gram‐negative and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 417 participants
Very low

Gram‐negative and anaerobic coverage vs gram‐positive, gram‐negative, and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 177 participants
Very low

More than 24 hours of antibiotics vs 24 hours of antibiotics

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes mortality compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
OR 1.67 [0.73, 3.82]
7 studies · 1261 participants
Very low

Gram‐positive and gram‐negative coverage vs gram‐negative and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether gram‐positive and gram‐negative coverage changes mortality compared with gram‐negative and anaerobic coverage (very low certainty).

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
OR 0.55 [0.11, 2.77]
3 studies · 555 participants
Very low

Single‐dose antibiotic vs 24 hours of antibiotics

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 360 participants
Very low

Anaerobic coverage only vs gram‐positive, gram‐negative, and anaerobic coverage

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

1 finding from 1 review

Prophylactic antibiotics for penetrating abdominal trauma: duration of use and antibiotic choice 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 309 participants
Very low