Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

Polyclonal T‐cell antibody induction vs interleukin‐2 receptor antagonist induction

All‐cause mortality · lung transplant recipients

Polyclonal T‐cell antibody induction showed no clear difference in mortality compared with interleukin‐2 receptor antagonist induction (moderate certainty).

1 finding from 1 review

Antibody induction therapy for lung transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.41 [0.55, 3.64]
3 studies · 100 participants
Moderate

Polyclonal T‐cell antibody vs no antibody induction

All‐cause mortality · lung transplant recipients

Polyclonal T‐cell antibody showed no clear difference in mortality compared with no antibody induction (moderate certainty).

1 finding from 1 review

Antibody induction therapy for lung transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.02 [0.71, 1.47]
3 studies · 125 participants
Moderate

Monoclonal antibody vs polyclonal antibody

Mortality Mortality at latest · heart transplant recipients

Monoclonal antibody showed no clear difference in mortality Mortality at latest compared with polyclonal antibody (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 1 [0.9, 1.1]
7 studies · 315 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

Mortality Mortality at latest · heart transplant recipients

Interleukin‐2 RA showed no clear difference in mortality Mortality at latest compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.1 [0.65, 1.88]
4 studies · 185 participants
Low