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Evidence found and GRADE certainty

8 questions · 9 findings · 2 reviews · Neonatal

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No studies found 5 · 55.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 22.2%Moderate 2 · 22.2%High 0 · 0%

Comparison 1: antibiotic alone or antibiotic with other newborn care interventions vs usual care

Neonatal mortality · neonates with sepsis

Comparison 1: antibiotic alone or antibiotic with other newborn care… showed no clear difference in neonatal mortality ‐ antibiotics alone compared with standard care (moderate certainty).

2 findings from 1 review

Summary of findings table ‐ Treatment of clinical and electrographic seizures vs treatment of clinical seizures alone

Mortality before hospital discharge · neonates

Summary of findings table ‐ Treatment of clinical and electrographic… showed no clear difference in mortality before hospital discharge compared with treatment of clinical seizures alone (low certainty).

1 finding from 1 review

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Neonatal mortality · neonates with fast breathing alone

Comparison 2: 7 days oral amoxicillin showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).

1 finding from 1 review