Findings

What do systematic reviews say?

24 questions · 24 findings · 11 reviews

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No studies found 10 · 41.7%GRADE not reported 4 · 16.7%Very low 5 · 20.8%Low 4 · 16.7%Moderate 0 · 0%High 1 · 4.2%

Oxytocin solution vs Normal saline

Maternal death · management of retained placenta

Oxytocin solution showed no clear difference in maternal mortality compared with saline solution (low certainty).

1 finding from 1 review

Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
RR 2.93 [0.12, 71.59]
5 studies · 782 participants
Low

Hyperimmune immunoglobulin from human plasma vs saline placebo

All‐cause mortality at day 28 · individuals with moderate or severe COVID‐19

Hyperimmune immunoglobulin from human plasma showed no clear difference in all‐cause mortality at day 28 compared with saline placebo (low certainty).

1 finding from 1 review

Hyperimmune immunoglobulin for people with COVID‐19 2023 · Cochrane Headline outcomes only
RR 0.79 [0.43, 1.44]
Studies not reported
Low

RBD‐specific polyclonal F(ab') 2 fragments of equine antibodies (EpAbs) vs saline placebo

All‐cause mortality (by day 28) · individuals with moderate or severe COVID‐19

RBD‐specific polyclonal F(ab') 2 fragments of equine antibodies… showed no clear difference in all‐cause mortality (by day 28) compared with saline placebo (low certainty).

1 finding from 1 review

Hyperimmune immunoglobulin for people with COVID‐19 2023 · Cochrane Headline outcomes only
RR 0.6 [0.26, 1.37]
1 study · 241 participants
Low

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

RECOVERY trial outcomes (mortality; hospitalisation status; use of ventilation; use of renal dialysis or haemofiltration) · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID‐19… 2020 · Cochrane All outcomes
Minimum 2 weeks
No data available (no included studies)
0 studies
No studies found