Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Progesterone vs no treatment or placebo (route of progesterone administration)

Miscarriage per clinical pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in miscarriage per clinical pregnancy compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.7 [0.4, 1.25]
5 studies · 261 participants
Low

Oral progesterone vs vaginal progesterone

Miscarriage per clinical pregnancy · women trying to conceive by intrauterine insemination

It is very uncertain whether oral progesterone changes miscarriage rate per clinical pregnancy compared with vaginal progesterone (very low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.58 [0.11, 3.09]
1 study · 41 participants
Very low

Progesterone vs placebo/no treatment

Miscarriage per clinical pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.67 [0.3, 1.5]
2 studies · 123 participants
Low

Progesterone vs placebo/no treatment

Miscarriage per clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation

Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.53 [0.25, 1.14]
2 studies · 119 participants
Low

Progesterone vs placebo/no treatment

Miscarriage per clinical pregnancy · women with gonadotropin stimulation

Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.68 [0.24, 1.91]
2 studies · 102 participants
Low