Findings

What do systematic reviews say?

6 questions · 7 findings · 1 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 3 · 42.9%Moderate 1 · 14.3%High 0 · 0%

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs no treatment or placebo

Menstrual blood loss: mean loss · women with heavy menstrual bleeding

1 finding from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 565 participants
Moderate

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs ethamsylate (control)

Menstrual blood loss: mean loss · women with heavy menstrual bleeding

1 finding from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs NSAIDs

Menstrual blood loss: mean loss · women with heavy menstrual bleeding

1 finding from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Progestogen 2

Menstrual blood loss: mean loss · women with heavy menstrual bleeding

1 finding from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 312 participants
Very low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs herbal medicines

Menstrual blood loss: mean loss · heavy menstrual bleeding

2 findings from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 121 participants
Low
Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs levonorgestrel intrauterine system

Menstrual blood loss: improvement in mean blood loss (PBAC score < 100) · heavy menstrual bleeding

It is very uncertain whether antifibrinolytics changes menstrual blood loss: improvement in mean blood loss (PBAC score <… compared with levonorgestrel intrauterine system (very low certainty).

1 finding from 1 review

Antifibrinolytics for heavy menstrual bleeding 2018 · Cochrane Headline outcomes only
RR 0.43 [0.24, 0.77]
1 study · 42 participants
Very low