Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

FVC · children with cystic fibrosis

Dornase alfa showed no clear difference in mean absolute change in FVC (L) at 3 months compared with mannitol (low certainty).

1 finding from 1 review

Dornase alfa for cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
231 participants
Low

FVC · children with cystic fibrosis

Dornase alfa showed no clear difference in mean absolute change in FVC (L) at 3 months compared with dornase alfa and mannitol (low certainty).

1 finding from 1 review

Dornase alfa for cystic fibrosis 2021 · Cochrane Headline outcomes only
MD 0.13
231 participants
Low