Group 3 Pulmonary hypertension due to lung disease ‐ PDE5i vs placeboPAP · people with pulmonary hypertension due to lung disease1 finding from 1 reviewPhosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 61 participantsModerate
Group 2 Pulmonary hypertension due to left‐heart disease ‐ PDE5i vs placeboPAP · people with pulmonary hypertension due to left‐heart disease1 finding from 1 reviewPhosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 130 participantsModerate
Group 4 Pulmonary hypertension due to CTEPH ‐ PDE5i vs placeboPAP · people with pulmonary hypertension due to CTEPH2 findings from 1 reviewPhosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 19 participantsLowPhosphodiesterase 5 inhibitors for pulmonary hypertension 2019 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 227 participantsModerate
Endothelin receptor antagonists vs placeboChange from baseline in mean PAP (mmHg) mean duration of study 17.1 weeks · pulmonary arterial hypertension1 finding from 1 reviewEndothelin receptor antagonists for pulmonary arterial hypertension 2021 · Cochrane Headline outcomes onlyno estimate extracted8 studies · 729 participantsModerate