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Evidence found and GRADE certainty

2 questions · 4 findings · 1 reviews · All outcomes

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Topical curcumin gel vs Topical aloe vera gel

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether topical curcumin gel changes maximal mouth opening (interincisal distance) compared with topical aloe vera gel (very low certainty).

1 finding from 1 review

Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

Antioxidants (lycopene, curcumin, Oxitard) showed no clear difference in maximal mouth opening (interincisal distance) compared with placebo or no active treatment (low certainty).

3 findings from 1 review