Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Antioxidants (lycopene, curcumin, Oxitard) showed no clear difference in maximal mouth opening (interincisal distance) compared with placebo or no active treatment (low certainty).
3 findings from 1 review
- MD -1.41 [-5.74, 2.92]1 study · 90 participantsLow
- MD 3.11 [0.46, 5.77]2 studies · 520 participantsLow
- MD 8.83 [8.22, 9.45]3 studies · 620 participantsModerate