Summary of Findings Table ‐ IncobotulinumtoxinA 20U vs placebo
Major adverse events · glabellar lines
1 finding from 1 review
- no estimate extracted2 studies · 547 participantsModerate
Findings
What do systematic reviews say?
4 questions · 4 findings · 1 reviews · Skin
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 100%High 0 · 0%
Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo
Major adverse events · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher major adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- OR 3.62 [1.5, 8.74]8 studies · 1390 participantsModerate
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U vs placebo
Major adverse events · glabellar lines
1 finding from 1 review
- no estimate extracted2 studies · 716 participantsModerate
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Major adverse events (eyelid ptosis, eyelid sensory disorder, strabismus) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in major adverse events (eyelid ptosis, eyelid sensory disorder,… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 3.36 [0.88, 12.87]7 studies · 1294 participantsModerate