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Evidence found and GRADE certainty

24 questions · 25 findings · 5 reviews

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No studies found 1 · 4%GRADE not reported 22 · 88%Very low 1 · 4%Low 0 · 0%Moderate 1 · 4%High 0 · 0%

Amifostine (intravenous) vs Amifostine (subcutaneous)

Locoregional control · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Amifostine (intravenous) showed no clear difference in locoregional tumour control compared with amifostine (subcutaneous); GRADE not reported.

1 finding from 1 review

Amifostine vs no treatment/placebo

Locoregional control · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Amifostine showed no clear difference in locoregional tumour control compared with no treatment/placebo; GRADE not reported.

1 finding from 1 review

Amifostine 200 mg/m2 three times weekly vs Amifostine 200 mg/m2 five times weekly

Survival (overall survival and locoregional control) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review