evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Musculoskeletal

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Folinic acid vs placebo

Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis

Folinic acid probably leads to lower liver toxicity (incidence of transaminase elevation) compared with placebo (moderate certainty).

1 finding from 1 review

Folic or folinic acid (any) vs placebo

Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis

Folic or folinic acid (any) probably leads to lower liver toxicity (incidence of transaminase elevation) compared with placebo (moderate certainty).

1 finding from 1 review

Summary of findings: Folic acid vs placebo

Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis

Folic acid probably leads to lower liver toxicity (ie, incidence of transaminase elevation) compared with placebo (moderate certainty).

1 finding from 1 review