What do systematic reviews say?

FLUPENTHIXOL vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS

• Flupenthixol versus low‐potency first‐generation antipsychotic drugs for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Benzodiazepines vs antipsychotics

It is very uncertain whether BENZODIAZEPINES changes leaving the study early due to any reason (overall acceptability of… compared with ANTIPSYCHOTICS (very low certainty).

• Benzodiazepines for schizophrenia 2012 · Cochrane Headline outcomes only
  RR 0.73 [0.45, 1.18]
  13 studies · 738 participants
  Very low

RISPERIDONE vs QUETIAPINE

RISPERIDONE showed no clear difference in leaving the study early: 1. any reason, long term (>12 months) compared with QUETIAPINE ‒ short‐ and long‐term data (low certainty).

• Risperidone versus other antipsychotics for people with severe mental illness and co‐occurring substance misuse 2018 · Cochrane Headline outcomes only
  RR 0.96 [0.86, 1.07]
  1 study · 294 participants
  Low

FLUPHENAZINE (ORAL) vs AMISULPRIDE

It is very uncertain whether FLUPHENAZINE (ORAL) changes leaving the study early ‐ any reason ‐ short term (up to 12 weeks) compared with AMISULPRIDE (very low certainty).

• Fluphenazine (oral) versus atypical antipsychotics for schizophrenia 2016 · Cochrane Headline outcomes only
  RR 1.19 [0.63, 2.28]
  2 studies · 98 participants
  Very low