Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Eyes and Vision

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Vitamin C vs placebo

Progression to late AMD (neovascular AMD, geographic atrophy or both) · general population

Vitamin C showed no clear difference in late AMD (either neovascular AMD or geographic atrophy or both) compared with placebo (moderate certainty).

1 finding from 1 review

Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
RR 0.94 [0.61, 1.46]
1 study · 14236 participants
Moderate

Vitamin E vs placebo

Progression to late AMD (neovascular AMD, geographic atrophy or both) · general population

Vitamin E showed no clear difference in late AMD (either neovascular AMD or geographic atrophy or both) compared with placebo (moderate certainty).

1 finding from 1 review

Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
RR 1.22 [0.89, 1.67]
4 studies · 55614 participants
Moderate

Beta‐carotene vs placebo

Progression to late AMD (neovascular AMD, geographic atrophy or both) · general population

Beta‐carotene showed no clear difference in late AMD (either neovascular AMD or geographic atrophy or both) compared with placebo (moderate certainty).

1 finding from 1 review

Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
RR 0.9 [0.65, 1.24]
2 studies · 22083 participants
Moderate