Fluorides combined with CPP-ACP vs Fluorides alone (monotherapy)
Laser fluorescence (LF) change · Patients with early caries lesions in permanent teeth (non-fluoridated water area)
For occlusal early caries lesions, adding CPP-ACP to fluorides produced significantly greater laser-fluorescence improvement than fluorides alone (favors the combination); not GRADE-rated.
2 findings from 1 review
- Efficacy of fluorides and CPP-ACP vs fluorides monotherapy on early caries lesions: A systematic review and… 2018 All outcomesPost-treatment (3-12 weeks) · In vivo clinical trial (human oral cavity; occlusal early caries lesions) · Location of lesions: occlusal surfacesMD -21.02 [-27.94, -14.10]3 studiesGRADE not reported
- Efficacy of fluorides and CPP-ACP vs fluorides monotherapy on early caries lesions: A systematic review and… 2018 All outcomesPost-treatment (12-24 weeks) · In vivo clinical trial (human oral cavity; smooth-surface early caries lesions) · Location of lesions: smooth surfacesMD -13.90 [-39.25, 11.46]4 studiesGRADE not reported