Orthodontic adhesives containing bioactive glass (BAG) particles/nanoparticles (including fluoride- or Ga-doped BAG) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control
Ion release (fluoride, calcium, phosphate) · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, among the 5 BAG ion-release studies only Ga-doped BAG (GaMBN, Song [31]) reported a significant increase (phosphate, up to 14 days); a general significant fluoride/calcium/phosphate increase across all 5 is not supported (ungraded).
1 finding from 1 review
- Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic brackets:… 2024 All outcomes14 days [31] and 20 days [27,28] (per Discussion); ion-release durations for [23,24] not reported · In vitro (laboratory) · OverallIon release from BAG-containing adhesives was assessed in 5 studies [23, 24, 27, 28, 31]; a significant increase of phosphate ion release with gallium-doped bioactive glass nanoparticles up to 14 days was reported…5 studiesGRADE not reported