Findings

What do systematic reviews say?

7 questions · 7 findings · 2 reviews · Wounds

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 2 · 28.6%High 0 · 0%

Topical antibiotics vs no topical antibiotic.

Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention

Topical antibiotics probably leads to lower surgical site infection compared with no topical antibiotic. (moderate certainty).

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
RR 0.61 [0.42, 0.87]
7 studies · 5427 participants
Moderate

Topical antibiotics vs antiseptic agent

Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention

Topical antibiotics probably leads to lower surgical site infection compared with antiseptic (moderate certainty).

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
RR 0.49 [0.3, 0.8]
4 studies · 1299 participants
Moderate

Iodine vs topical antibiotics

Infection · people with burns

The review found no eligible studies for this question.

1 finding from 1 review

Antiseptics for burns 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Silver‐based antiseptics vs topical antibiotics

Infection · people with burns

It is very uncertain whether silver‐based antiseptics changes infection compared with topical antibiotics (very low certainty).

1 finding from 1 review

Antiseptics for burns 2017 · Cochrane Headline outcomes only
RR 0.84 [0.48, 1.49]
4 studies · 309 participants
Very low

Aloe vera vs topical antibiotics

Infection: Aloe Vera versus SSD · people with burns

It is very uncertain whether aloe vera changes infection: Aloe Vera versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review

Antiseptics for burns 2017 · Cochrane Headline outcomes only
RR 0.93 [0.26, 3.34]
3 studies · 221 participants
Very low

Honey vs topical antibiotics

Peristent infection: honey versus SSD · people with burns

It is very uncertain whether honey changes peristent infection: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review

Antiseptics for burns 2017 · Cochrane Headline outcomes only
RR 0.1 [0.05, 0.19]
2 studies · 170 participants
Very low

Honey vs topical antibiotics

Incident infection: honey versus SSD or mafenide acetate · people with burns

It is very uncertain whether honey changes incident infection: honey versus SSD or mafenide acetate compared with topical antibiotics (very low certainty).

1 finding from 1 review

Antiseptics for burns 2017 · Cochrane Headline outcomes only
RR 0.16 [0.08, 0.34]
4 studies · 480 participants
Very low