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What do systematic reviews say?

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Evidence found and GRADE certainty

1 questions · 1 findings · 1 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 100%

Valproate vs placebo

Adverse effects: 1. Sedation · Adults (aged 18 and over) with acute mania

Valproate showed no clear difference in individual adverse events ‐ Sedation At 3‐8 weeks (secondary… compared with placebo (high certainty).

1 finding from 1 review