Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Emergency and Critical Care

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No studies found 1 · 20%GRADE not reported 1 · 20%Very low 1 · 20%Low 1 · 20%Moderate 1 · 20%High 0 · 0%

Oral midazolam vs placebo

Incomplete procedure · children requiring sedation before micturating cystourethrograms and Kirschner wire removal and adults undergoing flexible sigmoidoscopy

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 179 participants
Very low

Intravenous midazolam vs diazepam

Incomplete procedure · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 170 participants
GRADE not reported

Summary of findings ‐ Intranasal midazolam vs placebo

Incomplete procedure · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI

Intranasal midazolam showed no clear difference in incomplete procedure compared with placebo (low certainty).

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
RR 0.14 [0.02, 1.12]
2 studies · 149 participants
Low

Intravenous midazolam vs placebo

Incomplete procedure · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy

The review found no eligible studies for this question.

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral midazolam vs chloral hydrate

Incomplete procedure · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…

Oral midazolam probably leads to higher incomplete procedures compared with chloral hydrate (moderate certainty).

1 finding from 1 review

Midazolam for sedation before procedures 2016 · Cochrane Headline outcomes only
RR 4.01 [1.92, 8.4]
4 studies · 268 participants
Moderate