Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 1 · 33.3%

Incidence of typhoid fever – year 2 · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) probably leads to lower incidence of typhoid fever – year 2 compared with control (moderate certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.41 [0.31, 0.55]
4 studies · 194969 participants
Moderate

Cases of typhoid fever, Year 3 · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) may leads to lower incidence of typhoid fever –year 3 compared with control (low certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.5 [0.32, 0.78]
1 study · 11384 participants
Low

Incidence of typhoid fever – year 1 Blood culture · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) leads to lower incidence of typhoid fever – year 1 Blood culture compared with control (high certainty).

1 finding from 1 review

Vaccines for preventing typhoid fever 2018 · Cochrane Headline outcomes only
RR 0.31 [0.26, 0.37]
3 studies · 99797 participants
High