Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Acute gout attacks · patients with chronic cout

Febuxostat 120 mg/day probably leads to higher incidence of gout flares compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat for treating chronic gout 2012 · Cochrane Headline outcomes only
RR 1.7 [1.3, 2.3]
2 studies · 479 participants
Moderate

Acute gout attacks · people with chronic gout

Febuxostat 120 mg/day showed no clear difference in incidence of gout flares compared with allopurinol (high certainty).

1 finding from 1 review

Febuxostat for treating chronic gout 2012 · Cochrane Headline outcomes only
RR 1.3 [0.87, 1.9]
2 studies · 986 participants
High