Summary of findings ‐ withdrawal of penicillin prophylaxis vs continuation
Incidence of S pneumoniae Confirmed bacterial infection · children with SCD who have been receiving prophylactic penicillin for at least two years
Summary of findings ‐ withdrawal of penicillin prophylaxis showed no clear difference in incidence of S pneumoniae Confirmed bacterial infection compared with continuation (low certainty).
1 finding from 1 review
- Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease 2021 · Cochrane Headline outcomes onlyOR 0.49 [0.09, 2.71]1 study · 400 participantsLow