Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Dementia and Cognitive Improvement

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Incidence of Alzheimer's disease · people with MCI

The intervention probably leads to higher incidence of Alzheimer's disease (moderate certainty).

1 finding from 1 review

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia 2020 · Cochrane Headline outcomes only
RR 1.32 [1.01, 1.72]
1 study · 1457 participants
Moderate

Incidence of Alzheimer's disease · cognitively healthy people in late life

Other NSAIDs showed no clear difference in incidence of Alzheimer's disease compared with placebo (moderate certainty).

1 finding from 1 review

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia 2020 · Cochrane Headline outcomes only
RR 1.91 [0.89, 4.1]
1 study · 2125 participants
Moderate