Rifampicin vs isoniazid
Hepatotoxicity:13 Grade 3 and 4 toxicity · HIV‐negative people at risk of TB infection1
Rifampicin probably leads to lower hepatotoxicity:13 Grade 3 and 4 toxicity compared with isoniazid (moderate certainty).
1 finding from 1 review
- Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV‐negative… 2013 · Cochrane Headline outcomes onlyRR 0.15 [0.07, 0.4]5 studies · 1774 participantsModerate