Findings

What do systematic reviews say?

22 questions · 23 findings · 10 reviews

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No studies found 4 · 17.4%GRADE not reported 0 · 0%Very low 13 · 56.5%Low 4 · 17.4%Moderate 2 · 8.7%High 0 · 0%

Intervention not reported

Hearing loss · children and adults with acute bacterial meningitis

The intervention probably leads to lower hearing loss (moderate certainty).

1 finding from 1 review

Osmotic therapies added to antibiotics for acute bacterial meningitis 2018 · Cochrane Headline outcomes only
RR 0.64 [0.44, 0.93]
5 studies · 922 participants
Moderate

Different dosing regimens of aminoglycosides (daily vs 8 hourly)

Hearing impairment following treatment · children with acute pyelonephritis

Different dosing regimens of aminoglycosides (daily showed no clear difference in hearing impairment following treatment compared with 8 hourly) (low certainty).

1 finding from 1 review

Antibiotics for acute pyelonephritis in children 2014 · Cochrane Headline outcomes only
RR 2.83 [0.33, 24.56]
3 studies · 271 participants
Low